First pitch is scheduled for 6:45 p.m. at Busch Stadium.
Four games into the season, the Cardinals have yet to receive the performance from their starting rotation that they had hoped for. They will now turn to Steven Matz, the left-hander who missed much of last year with injury, to try and salvage this turn through the rotation before sending Miles Mikolas to the mound for the series finale. Matz will be charged with leading the effort to avoid a series loss.
The Cardinals will shake up the roster for the first time this season, realigning many of the pieces around the core of Paul Goldschmidt, Nolan Arenado and Willson Contreras, who will hit in their usual places.