Paul DeJong, Kolten Wong and center fielder Harrison Bader round out the starting eight for staff ace Carlos Martinez, who will look to keep the Reds and starter Homer Bailey down.
With Friday's 4-2 win, the Cardinals have knocked off the Reds five straight this year, 10 in a row and in 12 of their last 14 meetings. Cincinnati enters Saturday's action having won just three of 19 games to open the season, prompting the recent firing of manager Bryan Price. Jim Riggleman has taken over as interim manager.
Martinez (2-1, 1.75 ERA) is coming off a 3-2 win in Cincinnati on Sunday; in his fourth start of the season, he pitched seven innings, allowing two hits and no runs.