Starting pitcher Daniel Ponce de Leon, who was supposed to pitch on Saturday night and had his appearance pushed back after Friday's rain out, gave up four runs and left in the fifth inning after giving a home run, a double, and then hitting a batter. The double, by Joey Votto, turned out to be the winning run, though the Reds added one more run, on a home run by Phillip Ervin off reliever Mike Mayers in the sixth.
The Cardinals had taken a 3-2 lead in third, but the Reds tied the game on a leadoff homer by Nick Senzel in the fifth.