After falling behind Tuesday night, the Cardinals responded with two runs in the bottom of the first to take a 2-1 lead over the Cincinnati Reds at Busch Stadium.
After Matt Carpenter walked and Tommy Pham reached on an error, Jose Martinez moved the runners up with a one-out fly ball to deep right-center field. Yadier Molina ripped a 3-2 pitch from Reds starter Robert Stephenson into the left-field corner to drive in both runs.
On Sunday, Molina matched a career best with five RBIs in a 7-0 win over Pittsburgh.
The home team added to its lead in the second.