Yankuba Sima finished with 10 points in a win, while Mussini dropped 15 in Italy's victory.
Bracket play (the Round of 16) tipped off on Wednesday, as 16 teams had hopes of advancing to the 2016 U20 FIBA European Championship quarterfinals.
Yankuba Sima and Spain, who finished at 2-1 in group play, demolished Hungary (87-66) from tip-to-finish. Hungary had issues making the simply plays, turned the ball way too often, and lacked the bodies to compete with Spain's size and talent. Spain will take on Latvia (who beat Sweden by 13 in the Round of 16) on Friday in the quarters at 1:45 p.