Southern Miss (4-3, 2-1 CUSA) will look to bounce back after the Golden Eagles suffered their first conference loss of the season versus Louisiana Tech.
USM travels to Houston to face Rice (0-7, 0-3).
Here's what you need to know.
Southern Miss vs. Rice
When: 12 p.m. CST, Saturday, Oct. 26
Where: Rice Stadium, Houston, Texas.
How to follow: ESPN+, 104.5 (Hattiesburg)
Kickoff Weather: Mostly sunny, 70 degrees with winds northwest at 10 mph
The skinny
When Southern Miss and Rice take the field, it will be the ninth meeting between the two teams.