With the Conference USA tournament just two weeks away, the Golden Eagles were looking to continue their winning record with a win on the road against Rice.
In Game 1, Will McGillis was walked which was followed by a double from Matthew Guidry. Hunter Slater had an RBI groundout which brought McGillis home to give the Golden Eagles the lead.
Matt Wallner led off the fourth inning with a home run making, it his 15th for the season and 50th for his career.
Rice scored two runs in the bottom of the fifth inning but Southern Miss responded with three runs in the top of the sixth.