Southern Miss, in order to reach the Conference USA tournament championship game, has to beat UTSA twice Saturday.
The same UTSA team that defeated the Golden Eagles 7-6 early Friday.
Coach Scott Berry told his team late Friday it has "an opportunity to write a really, really good story if we can pull it off."
First pitch is set for 12:30 p.m. at Pete Taylor Park. If No. 12 Southern Miss (43-15) wins, it would see the Roadrunners again for a scheduled 7:30 p.m. first pitch.
Southern Miss baseball vs. UTSA score, live updates
Reach sports writer Jason Munz at jason.