Both the men and women defeated their Purple Aces counterparts by a score of 179-62 for the men and 191-46 for the women.
"It's a sentimental moment," coach Rick Walker said. "A lot of blood, sweat and tears go into just a few competitions. So, this one means probably the most to many just because it signifies a moving on, our graduation."
In the final women's event of the day, an all-senior team of Helena Amorim, Kiley Handley, Katy Ovington and Morgan Timms won the 100m freestyle relay with a time of 48.34.
"It was great to get all the girls together for just that one final race," Handley said.