Striker Ross Stewart "is chomping at the bit" to play his part against Leeds United on Saturday, according to Southampton manager Russell Martin.
The Saints travel to Elland Road for their final game of the Championship season with a play-off place secured.
Stewart signed from Sunderland on transfer deadline day last year but has only played 17 minutes this season.
"I want Ross to come on," Martin said. "He is chomping at the bit, now he has that opportunity he will get on the pitch all being well."
Stewart, 27, joined Southampton as he was recovering from an Achilles tendon issue and suffered a muscle injury in December.