Related Topics: Pep Guardiola, Riyad Mahrez, Kevin De Bruyne, Manchester City F.C., Raheem Sterling, FA Cup, Ibrahima Diallo, Phil Foden, Oriol Romeu, Southampton F.C.
Scroll down to see how it all unfolded with Sportsmail's live runner.
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16:53
FULL-TIME: Southampton 1-4 Man City
16:51
90 mins
Three minutes of added time.
16:49
85 mins
Riyad Mahrez drags a shot wide as he looks for his second.
Southampton make a couple more changes as Ibrahima Diallo and Will Smallbone come on for Mohamed Elyounoussi and Oriol Romeu.
