Manager Ivan Juric said Southampton will be relegated from the Premier League this season after watching his beleaguered side lose at home to 17th-placed Wolves at St Mary's.
The 2-1 defeat leaves Saints 17 points behind Vitor Pereira's team - and with a vastly inferior goal difference - with nine games left.
Southampton have now lost 24 of their 29 games this term and are only the fourth side in English top-flight history to lose nine consecutive home games in the same season, after Birmingham in 1985-86, Wolves in 2011-12 and Watford in 2021-22.