City beat the Foxes 3-1 last weekend and will be eager to follow up as they chase their third successive title.
However, with a 14-point gap between themselves and table-topping Liverpool they have a mountain to climb in the second half of the season.
City will be gunning for revenge having been beaten 2-0 by Wolves at the Etihad Stadium during October.
They have recorded victories in just two of their five previous Premier League games at Molineux, losing two and drawing the other.
A victory for Wolves this evening would take them up to fifth in the table, but City are fully expected to claim the three points.