Copa America, Group B
Venue: Estadio La Portada, La Serena
Kick-off: 8:00 p.m. BST/3:00 p.m. ET
Uruguay will be looking to finish their Group B campaign with a victory, which will ensure qualification for the quarter-finals.
The holders had looked uninspired in their laborious win over Jamaica, but the midweek defeat to Argentina was a blow.
Paraguay have proved to be one of the surprise packages of the 2015 Copa America after clawing their way back from two goals down to earn a draw with Argentina before beating Jamaica in their last match.