The first match of the weekend in Serie A is set up to be the most important one, as Sampdoria host leaders Juventus at 12 p.m. ET/5 p.m. BST.
All the three-time defending champions need from their excursion to the Stadio Luigi Ferraris to clinch the league title is one point.
Wrapping up the Serie A championship on Saturday would be a perfect momentum boost for the Old Lady of Italian football heading into Tuesday's UEFA Champions League semi-final first leg with Real Madrid, but Sampdoria will have something to say about that.
In the last league meeting between the two sides, Sampdoria claimed a point through a 1-1 draw in Turin.