The Dutch winger left the field holding his groin, having been named captain in Danny Blind's first competitive match as boss.
Bayern Munich winger Arjen Robben has limped out of Netherlands' Euro 2016 qualifying clash against Iceland with a suspected groin injury.
Robben, named captain in Danny Blind's first competitive match as Netherlands' manager, appeared to break down without contact from the opposition, before being withdrawn clutching his groin, after 32 minutes.
The former Chelsea and Real Madrid winger has a checkered history with injuries and could now miss the Netherlands' crucial qualifying match against Turkey on Sunday, with Luciano Narsingh the most likely to deputize.