The capital club are expected to rest many key figures for Saturday's clash as they prepare for Bayern Munich's visit in the Champions League
There may be nothing Real Madrid can do to stop Barcelona from winning La Liga this weekend, but Zinedine Zidane's men still have the fight for second place to keep in mind when they host Leganes on Saturday.
A 15-point difference between third-place Madrid and leaders Barca means the capital club have hardly been in the race this season and the Catalan side need just a draw from Sunday's trip to Deportivo to complete the formality.