The Portugal star is rested for his side's latest Liga test, as Zinedine Zidane rings the changes and gives Asensio a chance to shine up front
Cristiano Ronaldo will play no part in Real Madrid's latest Liga outing as the defending champions take on Espanyol on Tuesday.
Rested ahead of next week's Champions League clash against PSG, the Portuguese forward was left out of the Madrid squad that visits Barcelona midweek.
Marco Asensio is rewarded for his fine recent form with a place up front alongside Gareth Bale, with Karim Benzema left on the bench.
Zinedine Zidane makes a total of five changes from the side that beat Alaves on Saturday.