Isco was left out of Real Madrid's squad which faced AS Roma in the Champions League on Tuesday for showing a 'lack of respect' towards newly appointed manager Santiago Solari.
The Spain international travelled to the Italian capital with the rest of his teammates but was left in the stands following a bust-up with his new head coach.
Madrid-based radio station Cadena Cope claim that the pair's relationship is now 'broken' following their altercation over the weekend, where Los Blancos suffered a shocking 3-0 defeat against SD Eibar.
While Isco confirmed that he wasn't left out of the squad with an injury concern, Solari attempted to dodge questions surrounding the 26-year-old after their 2-0 win over Roma, insisting that the midfielder was dropped because of a sporting decision.