Lyon continued their impressive run over Paris Saint-Germain as they ended the Ligue 1 leaders' 21-match unbeaten run at the Groupama Stadium.
Moussa Dembele's header and a penalty from Nabil Fekir secured victory over Bruno Genesio's side after Angel di Maria had given the defending champions an early lead.
PSG are 10 points clear of Lille at the top and have seen their hopes of going the whole campaign without losing dashed.
Meanwhile, Lyon have a six-point cushion over fourth place Saint-Etienne in the race for the final Champions League spot.
2015 - Paris have lost a Ligue 1 game after scoring the opening goal for the 1st time since January 2015 against Bastia (2-4).