Everton host Liverpool at Goodison Park on Monday in the first Merseyside derby of the 2016-17 Premier League season.
Arsenal face a difficult task as they look to bounce back from their defeat at the hands of the Toffees, when they take on Manchester City at the Etihad Stadium on Sunday. Saturday's early kick-off will see Chelsea attempt to extend their league winning streak to 11 matches when they face Crystal Palace.
Elsewhere, Manchester United travel to West Bromwich Albion, Tottenham Hotspur welcome Burnley to White Hart Lane and, toward the bottom of the table, Middlesbrough play Swansea City and Hull City face West Ham United.