Hull City's dreams of Premier League survival were crushed at Crystal Palace, as they were defeated 4-0 on Sunday, triggering relegation.
The result also meant Eagles manager Sam Allardyce is once again the architect of a great escape, leading his club to safety with a game to spare.
Liverpool defeated West Ham United on the road, completing a 4-0 victory in east London to bolster their bid to secure UEFA Champions League football.
Later, Manchester United visited Tottenham Hotspur in the last game to be played at White Hart Lane before Spurs temporarily move to Wembley Stadium as the building of their new ground is completed.