Leicester City and Manchester City have the opportunity to gain some ground in the Premier League title race when they face off against one another on Saturday.
Leaders Liverpool are sitting out Week 18 as a result of their involvement in the FIFA Club World Cup.
Meanwhile, Jose Mourinho's Tottenham Hotspur will face off against his former side Chelsea on Sunday, after Manchester United have travelled to Watford.
Elsewhere, Everton host Arsenal while Aston Villa take on Southampton in a key survival clash.
Here's the schedule, complete with score predictions:
Saturday, December 21
Aston Villa vs.