Milan were eliminated from the Europa League on goal difference after a 3-1 loss, as Olympiakos produced an outstanding performance on a memorable night in Piraeus.
Olympiakos had a chance to score within the opening minute as Pepe Reina raced from his goal to deny Miguel Ángel Guerrero after a long ball sailed over his center backs. He was later called into action to push a Konstantinos Fortounis free kick around the post.
The Greek side had the lion's share of possession in the first half but it was Milan who looked more dangerous in the final third.