The NFL is back and there’s a full slate of games on Sunday. Here are our experts betting picks for NFL Week 1
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1. San Francisco 49ers (-9) on the Spread (-105) vs Detroit Lions
The San Francisco 49ers made it all the way to the Super Bowl 18 months ago but failed to reach the playoffs last season. Kyle Shanahan’s team was depleted through injury throughout 2020, missing big-name starters like QB Jimmy Garoppolo, DL Nick Bosa, RB Raheem Mostert, and WR Deebo Samuel (among others!