The Frenchman saw his spot kick stopped by Sergio Asenjo as they missed out on valuable points in the race to top the Spanish league
Samir Nasri missed a penalty as Sevilla were held to a 0-0 draw at home to Villarreal, losing ground on Real Madrid and Barcelona in La Liga's title race.
Do Madrid really need Ronaldo anymore?
Nasri produced a tame spot-kick that was easily saved by Sergio Asenjo down to his left four minutes into the second half, after Vitolo had been fouled by Mario.
The on-loan Manchester City playmaker is now without a goal since October.