The former Cardiff City midfielder replaces the injured Miranda alongside Jeison Murillo at the heart of the Nerazzurri defense, while Mauro Icardi is fit to start.
Gary Medel will start at center back for Inter in Sunday's derby clash with AC Milan at San Siro.
With Miranda having been ruled out with a knee problem, Nerazzurri coach Roberto Mancini has elected to pair former Cardiff City midfielder Medel with Jeison Murillo at the heart of the defense.
In a boost for Inter, Mauro Icardi has been passed fit to start, after missing the past two games through injury, and will line up alongside new arrival Ivan Perisic and summer signing Stevan Jovetic.