In a matchup that could be repeated in the Liguilla, Tigres UANL would get the better of Santos Laguna. Goals from Enner Valencia and André-Pierre Gignac and a red card to Matheus Doría would ensure the hosts would come away with all three points on the evening.
In the 14th minute, Tigres would score off of a corner kick when Javiér Aquino would chest down a ball to Enner Valencia, who would turn and fire past Jonathan Orozco. The Santos players were incensed, insisting Aquino had handled the ball but referee Erick Miranda declined to review the goal by VAR and the goal stood.