Wayne Rooney, Michael Carrick and Ashley Young all missed from the spot as Middlesbrough beat Manchester United in the League Cup.
Manchester United suffered another shock League Cup exit as it lost 3-1 on penalties to Middlesbrough following a 0-0 draw on Wednesday.
Louis van Gaal's much-changed side controlled the majority of the fourth-round tie, but it was Middlesbrough which created the best chances over 90 minutes, with Stewart Downing coming close and the recalled Daley Blind spared a remarkable own goal by the offside flag.
Jesse Lingard hit the woodwork for the home side and Sergio Romero twice saved superbly to deny Boro a dramatic late winner in normal time, after an earlier howler had come close to gifting the away side the lead.