Barcelona moved within touching distance of a second consecutive La Liga title as they beat Alaves 2-0 at Mendizorrotza on Tuesday.
Atletico Madrid now must earn at least a point at home to Valencia on Wednesday in order to make sure the title race continues into the weekend.
Second-half goals from Carles Alena and Luis Suarez ensured the Blaugrana extended their unbeaten run to 22 league games, and their lead at the top of the table now stands at 12 points.
Alena completed a superb move to break the deadlock in the 50th minute.