Pumas will face a tough test as they travel to Guanajuato to face Leon in their second away game of the season. Both teams arrive on the back of 1-0 wins, but the hosts Leon will have the advantage, as new Pumas signing Nicolas Castillo will be suspended for this match.
Pumas come into this game after their 1-0 victory against Cruz Azul, which broke a six-year winless streak at home against their tough city rival. Still, unlike the previous game against Chivas, the Universitarios largely struggled, even when they had a man advantage for most of the game.