Leon gave Pumas their first loss of the season when they defeated them by a score of 2-0 in a deserved but controversial loss. Pumas ended their undefeated streak in the same stadium and against the same team they had their last loss, in their final game of the Clausura 2020. Although Leon was the better team throughout the match, the game was marred when Pumas went down to ten players after Alfredo Talavera got a second yellow card. It was a dubious play that referee Cesar Ramos judged to be penalty kick even when replays showed it probably was the wrong call.