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Joao Felix netted his first La Liga goal since September, bagging the final goal in Atletico Madrid's comeback win over Villarreal.
The Rojiblancos fell behind early when Paco Alcacer opened the scoring but tied things up before the break and dominated in the second half.
Sevilla also collected all three points by beating Getafe, and Granada defeated Osasuna on the road.
Here are Sunday's results:
Osasuna 0-3 Granada
Alaves 2-1 Athletic
Valladolid 2-1 Espanyol
Getafe 0-3 Sevilla
Atletico Madrid 3-1 Villarreal
The standings for La Liga:
Atletico ran into an early deficit at home on Sunday, conceding the first goal after just 16 minutes.