Atletico Madrid host Barcelona on Sunday with a chance to climb level on points with La Liga's leaders if they emerge victorious, but Real Madrid can temporarily move clear at the top if they beat Alaves on Saturday.
Real Valladolid kicked off Week 15 with a visit to Celta Vigo on Friday when the two teams saw out a goalless draw Balaidos.
The stalemate was a fair result between two of the most goal-shy teams in Spain's top flight, with Celta stuck in the relegation zone while Valladolid moved one point closer to mid-table.
Real will liven matters up if they establish a new leader in La Liga on Saturday, travelling to Alaves with the target of ending Week 15 at the table summit.