Atletico Madrid's winless run in La Liga stretched to four games on Friday, as they were held to a 0-0 draw by Villarreal at El Madrigal.
Later this weekend, the league leaders will be expected to continue setting the pace, as Real Madrid and Barcelona have winnable home matches on Saturday against Espanyol and Real Mallorca, respectively.
There's a derby showdown between Levante and Valencia on the same day, before Sevilla head to Osasuna for the final fixture of the weekend
Here is the schedule in full for Week 16 and a recap of the action from Friday's showdown at Villarreal.