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Real Madrid's La Liga title bid will be put under pressure if Barcelona and Sevilla win in the season's 24th week. Both will be eager to take advantage of Los Blancos losing a game in hand 2-1 to Valencia on Wednesday, with the result opening up the title race.
Yet a win is far from certain for either side since Barca will face familiar thorn Atletico Madrid at the Vicente Calderon Stadium, while Sevilla are away to derby rivals Real Betis.
Real will be in the uncomfortable position of willing their local rivals to do them a favour.