Isco will play no part in Real Madrid's Copa del Rey semi-final second leg against Barcelona on Wednesday after being left out of the squad altogether by manager Santiago Solari.
The attacking midfielder has only recently returned from a back injury. However, despite participating in training this week, Solari hasn't included Isco in the group for the game at the Santiago Bernabeu, per MailOnline's Will Griffee.
Instead, Solari has trusted Marco Asensio and Dani Ceballos for the advanced areas of midfield.
In-form Vinicius Junior and Lucas Vazquez are available on the flanks for a game in which Real have the advantage of an away goal, having drawn the first leg 1-1 at the Camp Nou:
Real Madrid C.