Goals from Jonathan Biabiany, Mauro Icardi, Jeison Murillo and Marcelo Brozovic put Inter to the top of Serie A after a 4-0 win over Frosinone.
Inter moved back to the top of Serie A on Sunday courtesy of a 4-0 thrashing of Frosinone at San Siro.
Respective 2-2 draws for Fiorentina and Roma over the weekend opened the door for Roberto Mancini's side to resume top spot and it was in control throughout against the top-flight newcomer.
The home side was in charge right from the start and eventually turned first-half dominance into the lead when Jonathan Biabiany fired home on the rebound.