There is good and bad news for the Russian powerhouse ahead of its European clash, with the forward available for selection while the Argentine defender misses out.
Zenit coach Andre Villas-Boas has confirmed star forward Hulk will be fit to face Lyon in Wednesday's Champions League clash, although Ezequiel Garay will be absent.
Villas-Boas' side tops Group H with maximum points from three games, while Lyon props up the standings having drawn once and lost twice heading into the fourth matchday.
Hulk sat out of Zenit's 0-0 draw with Mordovia on Saturday with a groin strain, but Villas-Boas has alleviated concerns he will be absent versus Lyon, though Garay is definitely sidelined.