Manchester United travel to Chelsea in the glamour tie of the FA Cup on Monday, with the fifth-round matches taking place over four days.
Premier League champions Manchester City will expect an easy day at the office as they visit Newport County on Saturday.
Top-flight sides Brighton & Hove Albion and Crystal Palace are both in action. The teams take on Derby County and Doncaster Rovers, respectively.
Wolverhampton Wanderers will want to cap off a fantastic campaign with a significant cup run, with a trip to Bristol City facing the Molineux Stadium club.
Fifth-Round Matches and Score Predictions
Friday, Feb.