Liverpool manager Jurgen Klopp is set for an emotional return to Borussia Dortmund on Thursday, when he brings his new side to the Westfalenstadion for the first leg of their UEFA Europa League quarter-final.
The Reds will be hoping to become the first team to beat BVB in 2016, or at least come away with a positive result to build on for the return leg at Anfield.
Meanwhile, holders Sevilla will travel to La Liga rivals Athletic Club Bilbao as they seek to win the competition for the third year in a row, Sporting Braga will host Shakhtar Donetsk, and Villarreal welcome Sparta Prague to El Madrigal.