Ernesto Valverde revealed that Ousmane Dembele likely suffered a hamstring muscle tear during Barcelona's 2-0 defeat to Celta Vigo on Saturday.
The La Liga champions have already retained their title and fielded a heavily rotated side for the La Liga clash, as goals from Maximiliano Gomez and Iago Aspas condemned the visitors to a surprise defeat at the Balaidos.
Ousmane Dembele was among the names drafted into Barcelona's starting XI ahead of the second leg of their Champions League semi-final against Liverpool on Tuesday, but the Frenchman was forced off with an injury after just six minutes.