Mikel Arteta celebrated his first win as Arsenal manager on Wednesday following a 2-0 victory over Manchester United at the Emirates Stadium.
First-half goals from Nicolas Pepe and Sokratis Papastathopoulos were enough to give the Gunners all three points against a disappointing visiting side.
Elsewhere, Gabriel Jesus scored a brace for Manchester City as the defending champions returned to winning ways with a 2-1 victory over Everton at the Etihad Stadium.
Chelsea were held to a 1-1 draw at Brighton & Hove Albion, while Tottenham Hotspur suffered a surprise 1-0 defeat against Southampton at St Mary's Stadium.