Alexis Sanchez moved alongside Diego Costa as the most prolific goalscorer of the 2016-17 Premier League campaign, but he could not prevent Arsenal falling to a 2-1 defeat to Everton at Goodison Park on Tuesday.
A late Ashley Williams goal proved the knockout blow for the Gunners, as they lost their first game in the league since the opening day of the season, Seamus Coleman having cancelled out Sanchez's free-kick just before half-time.
In Tuesday's other Premier League game, Leicester were unable to build on their recent 4-2 drubbing of Manchester City, as they lost 1-0 to Bournemouth at the Vitality Stadium, with Marc Pugh netting the only goal of the match.