Stoke City became the first team to have their relegation from the Premier League confirmed this season after they fell 2-1 at home to Crystal Palace thanks to a late Patrick van Aanholt strike.
West Bromwich Albion preserved their top-flight status for at least a few more days after Jake Livermore bundled home an injury-time winner in their meeting with an out-of-shape Tottenham Hotspur side.
Swansea City's relegation scrap is still on after they lost 1-0 to Bournemouth at the Vitality Stadium, where Ryan Fraser's deflected goal stood as the difference.
West Ham United beat Leicester City 2-0 to clinch their first victory in five matches and essentially seal their Premier League status, while Watford beat Newcastle United 1-0 at home to move up to mid-table.