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Arsenal and Manchester City will do battle in the Premier League at the Emirates Stadium on Sunday, as both clubs attempt to salvage their domestic campaigns.
Liverpool welcome Everton to Anfield in the Merseyside derby on Saturday, with the Toffees in strong form and Romelu Lukaku developing into one of Europe's most dangerous strikers.
League leaders Chelsea cross swords with Crystal Palace at Stamford Bridge, as they attempt to extend their lead at the top of the division to 13 points.
Manchester United take to the stage at Old Trafford, with visitors West Bromwich Albion in superb shape under coach Tony Pulis.