The striker, along with Francesco Totti, is set for a spell on the sidelines after picking up an injury during Saturday's hammering of Carpi.
Roma has confirmed that Edin Dzeko will be out for between three or four weeks with a twisted knee.
The Bosian striker, who is on loan from Manchester City, picked up the injury during Saturday's 5-1 thumping of Carpi in Serie A and is now set to miss key fixtures for club and country.
Dzeko will miss Roma's Champions League game against BATE and the club's trip to Palermo, as well as the Euro 2016 qualifiers against Wales and Cyprus - but could return to face Empoli on Oct.