Cruz Azul surprised Pumas in their first game of the Copa GNP por Mexico, defeating the home side 4-1. Cruz Azul came in with a couple of players out of the game because of a rash of positive COVID-19 tests and yet were still able to beat Pumas. Despite having a squad that was closer to full strength and was playing at home although they had no fans, Pumas looked lost for most of the match. Cruz Azul got back from an early rough start to be the better side, as Pumas wilted and seemed to be the one making key mistakes when they had less youngsters on the field than the hampered Cruz Azul.