South Africa captain Janine Van Wyk was withdrawn from the clash with Malawi on Friday after picking up a knee injury.
The 32-year-old, who led Banyana Banyana to a four Cosafa Women's Cup titles, was left out for the second half after she suffered an injury from a poor challenge just before half-time.
The JVW star, who was making her first start in the competition, could not continue after and had to be replaced by Noko Matlou at the restart.
She was subsequently transferred to the hospital for further checks and undergo an MRI scan to ascertain the extent of her injury.