Pumas UNAM secured an entertaining 4-2 result over Emelec, while Penarol and Colo Colo managed 1-1 draws away from home.
Pumas kicked off their 2016 Copa Libertadores campaign with a rollercoaster 4-2 win over Emelec on Thursday.
The Mexican side took the lead after just 17 seconds thanks to Ismael Sosa before Angel Mena equalised for the Ecuadorians in the Group 7 clash. Dario Veron put Pumas back into the lead five minutes later, but they were reduced to 10 men when David Cabrera was sent off in the 64th minute.
Emelec used the man advantage to full effect three minutes later to equalize for a second time, but parity lasted just two minutes as Pumas struck again through Gerardo Alcoba two minutes later.